chronic pulmonary lung disease

chronic pulmonary lung disease

academic jour Journal of Tuberculosis and Respiratory Dise 2008 chronic obstructive pulmonary disease and pulmonary vascular endothelial cells and alveolar epithelial cell apoptosis in experimental study
Chronic obstructive pulmonary disease and pulmonary vascular endothelial cells and alveolar epithelial cell apoptosis in experimental studies Apoptosis of alveolar epithelial cells and pulmonary vascular endothelial cells in chronic obstructive pulmonary diseaseYou can in the "My Services" in the you add a reference to the notification list, and configure access to notices.Objective and smoke exposure in patients with COPD COPD pulmonary vascular endothelial cells and alveolar epithelial cells and its relationship with lung function and relevance of emphysema. Methods smoke exposure COPD rat models were established. COPD were collected patients (13 patients) and control patients (12 cases) and smoke exposure 80 d rats (11) and control rats (12) of the lung tissue samples assessed by HE staining of lung pathology, with an average interval lining (MLI) and the mean alveolar number (MAN) assess the degree of emphysema in rats; in situ end labeling of pulmonary vascular endothelial cells and alveolar epithelial cells for quantitative detection of apoptosis in these two correlation and its relationship with lung function and emphysema Indexes. normal distribution of measurement data to x s, said, using two independent samples t-test analysis; non-normal distribution of m

easurement data as median (interquartile bit spacing) that two independent samples using Wilcoxon rank sum test comparisons; using Spearman rank correlation were analyzed. Results COPD patients and rats were significant pathological changes of emphysema. COPD patients with pulmonary vascular endothelial cells and alveolar epithelial cells apoptotic index [(13.2 2.6)% and (28.9 3.1)%] was significantly higher than control patients [(5.6 1.5)% and (5.8 1.2)%]. COPD patients with alveolar epithelial cell apoptosis index [(28.9 3.1)%] was significantly higher than the index of pulmonary vascular endothelial cells [(13.2 2.6)%], positive correlation between them (r = 0.60, P of: LIU Shao-kun Chen Ping, CHEN Jian-bo to Xudong CAI Shan Deng Jianhua LIU Shao-kunCHEN PingCHEN Jian-boXIANG Xu-dongCAI ShanDENG Jian-hua LIU Shao-kun, CHEN Jian-bo, CAI Shan, LIU Shao-kun, CHEN Jian-bo, CAI Shan (Department of Respiratory Medicine, the Second Xiangya Hospital of Central South University, Changsha 410011, China)
Chen Ping, to Xudong, Deng Jianhua, CHEN Ping, XIANG Xu-dong, DENG Jian-hua (Department of Respiratory Medicine, Second Xiangya Hospital, Central South University, Changsha, 410011) Title: Chinese Journal of Tuberculosis and Respiratory Diseases ISTKU English title: CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES, the volume (of): 2008 31 (8) Key words: R5 Keywords: lung disease, chronic obstructive pulmonary endothelial cell apoptosis Pulmonary disease, chronic obstructive Endothelial cells Epithelial cells Apoptosis machine standard Keywords: R56 R54 machine standard Key words: chronic obstructive pulmonary disease and pulmonary vascular endothelial cells apoptosis of epithelial cells in alveolar epithelial cells Study obstructive pulmonary diseasevascular endothelial cellsalveolar epithelial cells apoptosis index of lung function induced pulmonary emphysema in smoke exposure in patients with negative correlation negative correlation between normal lung function measurement data Foundation item: National Natural Science Foundation of Hunan Province Graduate Innovation Project Grant of special funds DOI: References (9) credits of Chinese Medicine Respiratory Diseases, will study chronic obstructive pulmonary disease Group diagnosis and treatment of chronic obstructive pulmonary disease guidelines (revised 2007) [Papers] - Journal of Tuberculosis and Respiratory Diseases 2007, Chen Jinlong. Pi-Xin Ran vascular endothelial growth factor induced by smoke exposure and pathogenesis of emphysema [Papers] - Journal of Tuberculosis and Respiratory Diseases 2003 Demedts IK.Demoor T. Bracke KRRole of apoptosis in the pathogenesis of COPD and pulmonary emphysema 2006 Tuder RM.Wood K. Taraseviciene LCigarette smoke extract decreases the expression of vascular endothelial growth factor by cultured cells and triggers apoptosis of pulmonary endothelial cells 2000 (z1) Kanazawa H. Yoshikawa JElevated oxidative stress and reciprocal reduction of vascular endothelial growth factor levels with severity of COPD 2005 Barry M. Bleackley RCCytotoxic T lymphocytes: all roads lead to death 2002 Asymmetry. preserves Guisheng. Lin Li chronic obstructive pulmonary disease lung tissue changes in apoptosis and proliferation [Papers] - Journal of Tuberculosis and Respiratory Diseases 2005 Kasahara Y. Tuder RM.Taraseviciene-Stewart LInhibition of VEGF receptors causes lung cell apoptosis and emphysema 2000 Tang K . Rossiter HB.Wagner PDLung-targeted VEGF inactivation leads to an emphysema phenotype in mice 2004
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